Massive Study Pinpoints Ideal Time of Day For Exercise To Maximize Fat Loss And Other Benefits

Recent research led by Angelo Sabag and his team has uncovered compelling evidence on the importance of timing in physical activity for individuals dealing with obesity.

Published in the prestigious journal Diabetes Care, the study indicates that engaging in physical activity during specific times of the day can significantly impact health outcomes, particularly concerning mortality, cardiovascular disease (CVD), and microvascular disease (MVD).


This comprehensive study involved participants from the UK Biobank, focusing on adults with a body mass index (BMI) indicating obesity.

Researchers categorized physical activity into morning, afternoon, and evening sessions based on when participants undertook the majority of their moderate to vigorous physical activity (MVPA).

The study used sophisticated accelerometry data to capture and analyze physical activity levels, providing robust and objective measurements.

Statistical methods, including Cox proportional hazards regression models, were employed to estimate the risks associated with different timing of physical activity

Implications of the Study

The implications of these findings are significant, suggesting that the timing of physical activity could be a crucial factor in obesity management.

This insight could lead to revised guidelines that not only recommend regular physical activity but also suggest optimal timing to maximize health benefits.

Key Findings

The study’s results emphasize that the timing of physical activity plays a crucial role in health management for people with obesity. Here are some of the notable findings:

Mortality Rates: Individuals who performed their physical activities in the evening experienced the lowest risk of mortality, with a hazard ratio (HR) significantly lower compared to those who exercised at other times of the day.

Cardiovascular Disease: Similarly, the risk of cardiovascular events was lowest for those engaging in evening activities, reinforcing the potential benefits of timing physical exertion.

Microvascular Disease: The incidence of conditions such as nephropathy, neuropathy, and retinopathy was also reduced among participants active during the evening hours.


The study by Sabag and colleagues offers a groundbreaking perspective on the management of obesity through timed physical activities.

It highlights the potential of evening exercise to significantly lower the risk of death and disease in obese individuals.

Healthcare professionals might consider advising patients with obesity to schedule their exercise routines in the evening to reduce the risk of mortality and major diseases.

As these findings pave the way for further research, they underscore the need for a tailored approach in physical activity recommendations, one that could transform preventive health strategies and improve quality of life for those struggling with obesity.

This research not only enriches our understanding of the interplay between exercise and health outcomes but also acts as a catalyst for further studies that could affirm the best practices for incorporating physical activity into daily routines for those at risk of obesity-related conditions.


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